ABSTRACT
OBJETIVO: Descrever a implantação do teste de reflexo vermelho nas 30 cidades de inserção do Hospital das Clínicas da Faculdade de Medicina de Botucatu, HC/FMB/UNESP (480.337 habitantes), a criação de um centro para referência de crianças com reflexo vermelho alterado ou duvidoso, a Triagem do reflexo vermelho e outro para o tratamento da catarata infantil, o Centro de tratamento da catarata infantil. MÉTODOS: O exame do reflexo vermelho foi divulgado em 30 cidades da região de Botucatu. Foram realizadas palestras aos municípios, convocados pelo Departamento Regional de Saúde VI do estado de São Paulo (DRS VI). Foram distribuídos 109 "pen torch ophthalmoscope", às maternidades e Unidades Básicas de Saúde (UBSs) das cidades. A Triagem do reflexo vermelho recebeu os casos de reflexo vermelho alterado ou duvidoso e estabeleceu o diagnóstico oftalmológico. O Centro de tratamento da catarata infantil realizou o exame pré-operatório, o tratamento cirúrgico e o acompanhamento das crianças com catarata. RESULTADOS: Após um ano de funcionamento a Triagem do reflexo vermelho atendeu 29 crianças, 17 do sexo masculino e 12 do feminino, com idade média e desvio padrão (dp) de 10,09 ± 20,35 meses (7 dias - 98 meses). 16 pacientes foram encaminhados com reflexo vermelho alterado, idade média e dp de 13,17 ± 24,14 meses (7 dias - 98 meses), a alteração foi confirmada em todos os casos, 13 deles apresentavam catarata. Em 13 encaminhamentos com reflexo duvidoso, idade média e dp de 6,29 ± 14,46 meses (7 dias - 98 meses), a alteração não se confirmou. A incidência de alterações do reflexo vermelho encontradas foi de 9,2/10.000 nascidos vivos e a incidência the catarata foi de 7,9/10.000 nascidos vivos. CONCLUSÃO: Descrevemos a implantação do Teste do reflexo vermelho na Região de Botucatu, a criação da Triagem do reflexo vermelho e do Centro de tratamento da catarata infantil e dificuldades encontradas.
PURPOSE: To describe the implantation of the red reflex test in 30 cities in the area of Botucatu Medical School Clinical Hospital, (480,337 inhabitants) and the creation of a reference Center for children with red reflex changes, the Red reflex screening and another Center for treatment of childhood cataract. METHODS: The red reflex exam was released in 30 cities of the surrounding Botucatu area, lectures were done in the cities invited to participate by the Regional Department of Health.109 pen torch ophthalmoscopes were distributed to the hospital maternities and primary care units. The Red reflex screening attended cases of altered or doubtful red reflex and established the diagnosis. The Center for treatment of childhood cataract performed the preoperative examination, surgical treatment and follow-up of children with cataracts. RESULTS: After one year the Red reflex screening attended 29 children, 17 males and 12 females, mean age and pattern deviation (PD) of 10.09 ± 20.35 months (7 days - 98 months old). 16 patients were referred with altered red reflex, with a mean age and pattern deviation of 13.17 ± 24.14 months (7 days - 98 months old). The alteration was confirmed in all of these cases. 13 children had cataract. In 13 children with doubtful exam, with a mean age and PD of 6.29 ± 14.46 months (7 days - 54 months old), the alteration was not confirmed in any of these patients. The incidence of negative red reflex found among newborns was 9.2/10,000 and the incidence cataracts in this same group was 7.9/10,000. CONCLUSION: We described the implantation of the red reflex exam in the Botucatu area, and the creation of a reference Center for eye examination of children with changes in the red reflex, and the creation of a reference Center for treatment of childhood cataract and difficulties.
Subject(s)
Child , Child, Preschool , Female , Humans , Infant , Infant, Newborn , Male , Cataract/diagnosis , Eye Diseases/diagnosis , Reflex/physiology , Vision Screening/methods , Cataract/congenital , Cataract/therapy , Eye Diseases/congenital , Eye Diseases/therapy , Pigmentation , Visual AcuityABSTRACT
Se realizó un estudio descriptivo y longitudinal de 53 pacientes de 0-19 años de edad, con glaucoma del desarrollo, operados mediante trabeculectomía en el Servicio de Oftalmología del Hospital Infantil Sur de Santiago de Cuba desde 1999 hasta 2010, para lo cual se determinaron las características generales del diagnóstico, tratamiento quirúrgico y seguimiento médico integral, este último nunca inferior a un lustro después de la intervención. Se tomaron en cuenta desde los primeros síntomas referidos hasta la rehabilitación óptica y se compararon los resultados de la técnica en todos los integrantes de la casuística, de donde se derivó que fue efectiva en 69,0 por ciento de ellos. También se proporcionan otros datos clínicos y sobre la atención brindada a los niños y adolescentes que padecían la enfermedad.
A descriptive and longitudinal study of 53 patients aged between 0 and 19 years old with growth glaucoma surgically treated through trabeculectomy at Ophthalmology Service from the Southern Children Hospital in Santiago de Cuba was carried out from 1999 to 2010. General characteristics of diagnosis, surgical treatment, and comprehensive follow-up were determined. The latter was never lower than a lustrum after the intervention. First symptoms referred to optical rehabilitation were taken into account. Results of this technique applied in all the members of the case material were compared, from which it was derived that this technique was effective in 69,0 percent of them. Furthermore, other clinical data as well as some related to the health care offered to children and teenagers undergoing this sickness are provided.
Subject(s)
Humans , Male , Female , Child , Glaucoma/surgery , Glaucoma/rehabilitation , Eye Diseases/congenital , Secondary Care , Trabeculectomy , Epidemiology, Descriptive , Longitudinal StudiesABSTRACT
There are many techniques for treating congenital blepharoptosis. A new surgical technique for ptosis with poor levator function in which Seiff Silicone Suspension set is used in frontalis sling procedure is described in a 12 year old female child with simple unilateral congenital blepharoptosis. This procedure requires less surgical time, provides good cosmesis and early recovery.
Subject(s)
Blepharoptosis , Eye Diseases/congenitalABSTRACT
PURPOSE: To investigate the clinical features of Korean patients with congenital aniridia. METHODS: This retrospective study focused on 60 eyes from 31 patients who were diagnosed with congenital aniridia at Kangnam St. Mary's Hospital from 1996 to 2007. Patient age, gender, visual acuity (VA), family history, and previous ocular history were recorded. The presence of keratopathy, glaucoma, cataract, foveal hypoplasia, and other ocular or systemic anomalies were evaluated for each patient. RESULTS: The proportion of sporadic cases was 29.0%. Cataract (82.5%), glaucoma (51.6%), keratopathy (71.6%), and foveal hypoplasia (81.8%) commonly accompanied aniridia. Thirty-four (60.7%) eyes had VAs less than 20/200 and 20 eyes (35.7%) had VAs between 20/200 and 20/60. In patients without a past history of ocular surgery, the mean central corneal thickness was 643.05 +/- 37.67 microm and the mean endothelial cell count was 3,349.44 +/- 408.17 cells/mm2. Ocular surface surgeries were performed in 6 eyes. The clarity of the transplanted corneal graft vanished in 5 eyes with the progression of peripheral neovascularization and subepithelial fibrosis. The mean age of cataract surgery in 8 eyes was 29.8 +/- 5.9 years. Postoperative worsening of corneal clouding and glaucomatous damage were observed in 4 eyes. Two infants had bilateral congenital glaucoma. Two children with sporadic aniridia were identified to have Wilm's tumors. CONCLUSIONS: Congenital aniridia is a progressive congenital disorder that is commonly accompanied by complications that can lead to impaired vision. Regular, careful examinations for these accompanying complications should be performed in all patients with congenital aniridia.
Subject(s)
Adolescent , Adult , Child , Child, Preschool , Female , Humans , Infant , Male , Middle Aged , Aniridia/epidemiology , Comorbidity , Eye Diseases/congenital , Republic of Korea/epidemiology , Retrospective Studies , Visual AcuitySubject(s)
Blepharophimosis/complications , Child, Preschool , DNA Mutational Analysis , Eye Diseases/congenital , Family , Female , Forkhead Transcription Factors/genetics , Humans , India , Infant , Male , Mutation , Pedigree , SyndromeABSTRACT
Persistent hyperplastic primary vitreous [PHPV] is an idiopathic congenital malformation confined to the eye that has no obvious cause and that is usually unilateral and sporadic. The clinical features of the classic PHPV syndrome include white, vascularized tissue covering some or all of the posterior surface of the lens; centrally dragged ciliary processes; secondary glaucoma caused by swelling of the lens or caused by contracture of the retrolental tissue, with anterior shifting of the lens-iris diaphragm; extensive intravitrael hemorrhaging; persistence of the hyaloid artery; and occasionally retinal detachment. In the present study we describe a patient with bilateral PHPV unassociated with other diseases. A normal milestone of development was reported. Family pedigree analysis revealed similarly affected father, grandfather, 2 aunts, 1 uncle from paternal side, also a grand uncle with 2 affected daughters. On examination; height, weight, skull circumference were in 5[th] percentile. Bilateral B and A eye scan ultrasonography for both the patient and the father revealed picture suggestive of persistent hyperplastic primary vitreous. Cytogenetics study by conventional culture technique using CTG banding technique revealed normal male karyotype [46, XY] for both of them. Review of London Dysmorphology Data Base [LDDB], OMIM, and recent medical literature revealed that this case to our knowledge represents the second report supporting autosomal dominant inheritance of PHPV unassociated with other anomalies
Subject(s)
Humans , Male , Cytogenetic Analysis , Eye Diseases/congenitalABSTRACT
OBJECTIVE: To identify genetic disorders associated with ophthalmologic abnormalities; type and frequency of various ophthalmologic abnormalities associated with selected genetic and inherited disorders; and devise a suitable classification for ophthalmologic abnormalities. METHODS: Pediatric cases referred with mental retardation, congenital malformations and suspected genetic and metabolic disorders were enrolled prospectively. Relevant clinical details (including an ophthalmologic examination) and investigations were recorded. RESULT: Of the 1308 patients enrolled, 679 (51.9%) had ophthalmologic abnormalities. 458 cases (67.45%) out of these 679 had mental retardation and 20 (2.94%) had neuroregression. Environmental (12.22%) and chromosomal anomalies (10.9%) were the largest etiological groups. Down syndrome was the commonest of the chromosomal anomalies and mongoloid slant and epicanthic folds were its commonest ophthalmologic features. Mucopolysaccharidoses (21.4%), Wilson disease (19.64%), oculocutaneous albinism (16.07%) and lipid storage disorders (14.29%) were the most common inborn errors of metabolism associated with ophthalmologic abnormalities. Of the 39 cases with Mendelian inheritance of disorders, autosomal dominant disorders (56.41%) were the commonest associated with ocular abnormalities. A simple anatomical classification has been devised for various ophthalmologic abnormalities encountered (wherein, positional and adnexal abnormalities were the commonest). CONCLUSION: Up to 50% of cases referred to the genetic services have ophthalmologic abnormalities. Conditions including chromosomal abnormalities, metabolic disorders, Mendelian syndromes and environmental factors are associated with ocular abnormalities. Anatomically, positional and adnexal abnormalities are the commonest.
Subject(s)
Adolescent , Child , Child, Preschool , Down Syndrome/complications , Eye Diseases/congenital , Humans , Infant , Infant, Newborn , Metabolism, Inborn Errors/complications , Prospective StudiesABSTRACT
Se evaluó la incidencia de alteraciones oculares en infantes nacidos de madres con titulación positiva contra el complejo TORCH y la infección por sífilis. Incluimos a 33 pacientes, captados en el periodo de septiembre de 1997 a junio de 1998. Se valoró la presencia de alteraciones oculares congénitas en infantes con antecedentes de infección intrauterina por el síndrome de TORCH. Se incluyeron 8 mujeres (24.2 por ciento) y 25 hombres (75.7 por ciento). Las lesione que más se encontró fue: catarata en 6 pacientes (18.1 por ciento), coloboma en 2 pacientes (6.0 por ciento), microftalmía, entropión, queratoconjuntivitis, masa retrobulbar, desprendimiento de retina, coriorretinitis y atrofia óptica en los restantes pacientes (3.0 por ciento). Las infecciones intrauterinas influyen en el dessarrollo del ojo. Estos datos sugieren que el diagnóstico temprano de tales infecciones por el complejo TORCH permite realizar el tratamiento adecuado
Subject(s)
Humans , Male , Female , Infant, Newborn , Toxoplasmosis/complications , Toxoplasmosis/embryology , Toxoplasmosis/physiopathology , Cytomegalovirus Infections/congenital , Cytomegalovirus Infections/physiopathology , Herpesviridae Infections/embryology , Herpesviridae Infections/physiopathology , Rubella Syndrome, Congenital/embryology , Rubella Syndrome, Congenital/physiopathology , Pregnancy Complications, Infectious/diagnosis , Pregnancy Complications, Infectious/etiology , Immunoglobulin G , Immunoglobulin M , Eye Diseases/congenital , Eye Diseases/diagnosis , Syphilis, Congenital/diagnosis , Syphilis, Congenital/physiopathologyABSTRACT
La displasia facio-dígito-gential o Síndrome de Aarskog, es un padecimiento raro que se trasmite en forma recesiva ligada al cromosoma X. Presenta alteraciones faciales típicas asociadas a estatura baja, sindactilia, hernia inguinal y escroto en manto. Las manifestaciones oculares forman parte importante del diagnóstico de esta enfermedad y con frecuencia pasan inadvertidas. En este artículo presentamos las alteraciones oculares encontradas en una familia con Síndrome de Aarskog y se discute la importancia de una valoración oftalmológica adecuada
Subject(s)
Humans , Male , Female , Adolescent , Astigmatism/etiology , Blepharoptosis/etiology , Strabismus/etiology , Eye Diseases/congenital , Genitalia/abnormalities , Hypertelorism/etiology , Abnormalities, Multiple , SyndromeABSTRACT
Se presenta un caso de glioneuroma de órbita izquierda asociado a anoftalmía bilateral y quiste meníngeo, en un recién nacido con múltiples anomalías congénitas y con historia familiar de retraso mental y disontogenias. El glioneuroma es una neoplasia benigna constituida por células gliales, neuronas y un neurópilo de fondo. Se demostró el componente astroglial y clasmatodendrítico por medio de técnicas histoinmunoquímicas
Subject(s)
Humans , Male , Infant, Newborn , Anophthalmos , Neoplasms, Neuroepithelial/classification , Neoplasms, Neuroepithelial/congenital , Neoplasms, Neuroepithelial/pathology , Eye Diseases/congenital , Eye Diseases/pathology , Abnormalities, Multiple , ImmunohistochemistryABSTRACT
Analysis of 1;000 new paediatric eye patients over a one year period showed that conjunctival diseases were the commonest as opposed to refractive error found a decade ago. More cases of eye injuries; neuro-ophthalmological conditions; squints and congenital abnormalities were also encountered. Females attend hospital more readily than males constituting 50.9 per cent and 29.8 per cent of new patients seen were children 16 years and below. Uveitis and chronic open angle glaucoma were uncommon compared to adult patients. Trachoma was not found in this environment as opposed to Nothern Nigeria. Some of these eye diseases cause blindness which can be prevented if suggested steps are taken. The demand on specialist services could be reduced if eye care delivery is incorporated into primary health care programme
Subject(s)
Blindness/prevention & control , Conjunctival Diseases , Eye Diseases , Eye Diseases/congenital , Eye Injuries , Glaucoma , Infant , Lakes , Nigeria , Ophthalmic Assistants , Primary Health Care , Strabismus , TrachomaABSTRACT
A rare case of histopathologically proved case of congenital cystic eye in a one day old girl is described. It was an unusually large cystic mass bulging forwards stretching the upperlid. There was no rudimentary eyeball in the orbit. The cystic eye's predilection for the left eye has been pointed out for the first time in this article.